2006 Ram 1500 Quad Cab 4X4 (not sure if it changes anything but it is the Big Horn)

Its my brother in law's truck. He hit a pot hole at 65 mph and bent the rear driver side whell. Replaced it and again hit another pothole at 75 mph bending the rim again. New rim but now he has a heavy vibration from from the same side. Tires all balanced still a heavy vibration.

Bent axle shaft? Or something else?

 

an axle sounds most likely...mustsa been a helluva hole